Assuming that the security issue has gained additional complexity and importance due to the COVID-19 disease that pandemically marked our time, the basic goal of this paper is to emphasise the benefits of establishing an adequate international treaty regime on pandemic preparedness as a response to this ongoing health and safety challenge of global proportions. The establishment of an international pandemic treaty framework under the auspices of the World Health Organization could enable individual countries to improve their capacity to act more productively in terms of preparedness and responsiveness to new security threats. The results of this research will show that the adoption of such a universal legal instrument would contribute to the greater transparency and accountability of the international response to security threats of this kind, as well as to more coordinated action of the international community in terms of early detection, warning and response to future pandemics.